Isotopically Labeled Compounds
Medchemexpress LLC Nilutamide-d6 | 1189477-66-4 | 99.8% | 323.26 g/mol | C12H4D6F3N3O4 | 5 MG
Nilutamide-d6 is the deuterium-labeled isotopologue of nilutamide supplied as a stable isotope reference standard for analytical and research applications. It is intended for use as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS in studies of androgen receptor pharmacology. For research use only; not for human or clinical use.
- High isotopic labeling (D6) for reliable internal standardization.
- Suitable as tracer and internal standard for NMR, GC-MS, and LC-MS.
- High purity (99.8%) for accurate quantitation.
- Available in small mg pack sizes for analytical workflows.
Medchemexpress LLC Lansoprazole-d4 | 934294-22-1 | MFCD06658717 | 99.8% | 373.39 | C16H10D4F3N3O2S | 5 MG
Lansoprazole-d4 is a deuterium-labeled analogue of lansoprazole intended as a stable-isotope internal standard for analytical and research use. It is designed for quantitative mass spectrometry, pharmacokinetic studies, and method development to support accurate measurement of lansoprazole in biological and chemical matrices. The compound contains four deuterium atoms and is supplied with high purity for analytical workflows.
- Deuterium-labeled (d4) analogue for use as an internal standard.
- High purity for reliable analytical results.
- Suitable for LC-MS/MS and GC-MS quantification.
- Enables accurate pharmacokinetic and bioanalysis studies.
- Supplied in small milligram quantities for analytical workflows.
- Molecular weight 373.39 and CAS 934294-22-1 for unambiguous identification.
Medchemexpress LLC Tolcapone-d4 (ro 40-7592-d4) | 1246816-93-2 | 99.1% | 277.27 | 1 MG
Tolcapone-d4 (Ro 40-7592-d4) is the deuterium labeled Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50 of 773 nM. Tolcapone can inhibit α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Indole-d7 | 73509-20-3 | 124.19 | 5 MG
Indole-d7 is the deuterium labeled Indole, an endogenous metabolite. It serves as a valuable tool for quantitative analysis in various spectroscopic methods, including NMR, GC-MS, and LC-MS. The deuteration of Indole-d7 holds significance due to its potential influence on the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Endogenous metabolite
- Suitable for tracer applications
- Internal standard for quantitative analysis
- Used in NMR, GC-MS, and LC-MS
- Potential for pharmacokinetic and metabolic studies
Cayman Chemical HygromycIn B-d4 1mg
An internal standard for the quantification of hygromycin by GC- or LC-MS
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | 99.1% | 705.81 | 1 MG
Posaconazole-d5 is a deuterium-labeled form of Posaconazole, a broad-spectrum triazole compound with antifungal activity. This compound is suitable for various quantitative analyses and as a tracer in research applications.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Broad-spectrum antifungal activity
Medchemexpress LLC (±)-Nornicotine-d4 | 66148-18-3 | 152.23 | 100 MG
(±)-Nornicotine-d4 is the deuterium labeled (±)-Nornicotine, a major metabolite of Nicotine. It functions as a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. This compound is suitable for research applications in various fields.
- Disrupts β-catenin and ZO-1
- Induces F-actin depolymerization
- Supports self-administration behavior
- Applicable in research for atherosclerosis, Alzheimer's disease, and schizophrenia
Revvity Health Sciences Inc 3H Low Level Quenched Standards, 20 mL Vial
3H Low Level Quenched Standards, 20 mL Vial
Medchemexpress LLC Diflunisal-d3 | 1286107-99-0 | 99.7% | 253.22 | 2.5 MG
Diflunisal-d3 is the deuterium labeled form of Diflunisal, a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties. It acts as a Cyclooxygenase (COX) inhibitor and is used as an analgesic and in rheumatoid arthritis patients. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC DL-cystine-d6 | 352431-53-9 | MFCD01317433 | 99.8% | 246.34 | C6H6D6N2O4S2 | 10 MG
DL-cystine-d6 is the deuterium-labeled analog of DL-cystine supplied as a stable isotope standard for laboratory research. It is intended for analytical applications such as internal standardization, tracer studies, and quantitative mass spectrometry assays.
- Deuterium-labeled stable isotope of DL-cystine.
- High purity (99.81%).
- Molecular formula C6H6D6N2O4S2; molecular weight 246.34.
- Suitable as an internal standard for mass spectrometry and quantitative analysis.
- Supplied in small, preweighed quantities for analytical use.
- For research use only; not for human or clinical use.
Medchemexpress LLC L-Threonine-d5 | 1217456-38-6 | CB71121697 | 124.15 | 5 MG
L-Threonine-d5 is the deuterium labeled L-Threonine, a natural amino acid produced by microbial fermentation and used in food, medicine, or feed applications. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during drug development, potentially influencing pharmacokinetic and metabolic profiles. This compound can serve as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Deuterium labeling can influence drug pharmacokinetics and metabolic profiles
- Produced by microbial fermentation
Medchemexpress LLC Bictegravir-15N,d2 | 99.0% | 452.39 | 1 MG
Bictegravir-15N,d2 | 99.0% | 452.39 | 1 MG
Medchemexpress LLC L-Glutamine-15N-1 | 59681-32-2 | 147.14 | 5 MG
L-Glutamine-15N-1 is the 15N-labeled L-Glutamine. L-Glutamine is a non-essential amino acid found abundantly throughout the body and is involved in numerous metabolic processes. It serves as a carbon source for oxidation in certain cells.
- This compound can be utilized as a tracer.
- It can also be employed as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
- Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Sucralose-d6 | 1459161-55-7 | 403.67 | 1 MG
Sucralose-d6 is deuterium labeled Sucralose. Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.